产品名称：滨蒿内酯
CAS号  120-08-1
英文名称：6,7-Dimethoxycoumarin
分子式 C11H10O4
分子量 206.19

属性
溶解性 Soluble in DMSO (15 mg/ml), and water (partly miscible).
熔点 143-145°C
密度 1.2480
描述
别名 蒿属香豆素;Scoparone;6,7-Dimethylesculetin;6,7-Dimethoxy-2H-chromen-2-one;6,7-Dimethoxy-2-benzopyrone
产品介绍 Scoparone is a compound found in the herb, Yin Chin, that can up-regulate the expression and activate the CAR (constitutive androstane receptor) found in the liver. It has been shown to clear the accumulation of bilirubin by the activation of CAR in neonatal jaundice. Other studies show that scaparone inhibits lipopolysaccharide (LPS)-induced tissue factor (TF) expression in HUVECs and that it acts as an anti-inflammatory compound. TCPOBOP also transactivates CAR, however, scoparone can activate murine and human CAR. Scaparone can increase dopamine release by synapsin I phosphorylation through activation of PKA and CaMKII? in PC12 cells. It can also activate neurite outgrowth and improve dopamine biosynthesis in PC12 cells.
用途 An agent that can up-regulate the expression and activate CAR
包装 D101245-10mg in glass bottle