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7-乙基-10羟基喜树碱

产品名称:7-乙基-10羟基喜树碱

英文名称7-Ethyl-10-hydroxycamptothecin

CAS号   86639-52-3

分子式 C22H20N2O5 

分子量392.40









属性
存贮条件 储存温度2-8℃
熔点 217°C
密度 1.6000
旋光率 21.5 ° (C=0.2, THF)
描述
别名 SN-38
生化机理 Active metabolite of irinotecan. Inhibitor of topoisomerase I.. Gene expression analysis of colon cancer cell lines treated with SN-38 showed differential effects: the majority of affected genes were down-regulated (including, most strongly, genes related to receptor and kinase activity, signal transduction, apoptosis, RNA processing, protein metabolism and transport, cell cycle and transcription. Some of the up-regulated genes were involved in apoptosis, transcription, development and differentiation.
包装 E110128-1g,E110128-100mg in glass bottle

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